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The Australian National University
The John Curtin School of Medical Research
Microscopy and Cytometry Resource Facility

Histology (MCRF)

Contact:
Anne Prins
Level 2, Room B2030 and Room B2019

T:+61 2 6125 4644
F:+61 2 6247 4823
E:Anne.Prins@anu.edu.au
Mail address:
EM/Histo/Facs-Unit, JCSMR
GPO Box 334
Canberra City ACT 2601 Australia


The word histology originally meant "the study of science of tissues" although now, it is taken to mean "the study of the fine structure of animal tissues and organs". The basis of good histological preparations is adequate and complete fixation or preservation of the tissues. Fixation is necessary to prevent post mortem changes ie. autolysis, putrefaction and to preserve the tissue in as life like a manner as possible. It also hardens the naturally soft tissues so that they will be easily handled during the subsequent treatments and leaves the tissues in a state which facilitates differential staining with dyes and other reagents.